Philippine E-Journals

The role of bariatric and metabolic surgery on mildly obese diabetic patients

Katherine G. Ordinario | Emmanuel S. Astudillo

 

Abstract:

Introduction Bariatric surgery has been incorporated in the care of diabetic patients with a body mass index greater than 35 kg/m², however a segment of the diabetic population has a body mass index 30 to < 35 kg/m² that compared bariatric surgery with non-surgical management were considered in this study. The primary outcomes of interest were remission of diabetes mellitus, changes in body mass index, glycosylated hemoglobin and fasting blood sugar levels and in weight. The odds ratio was the primary measure of treatment effect; 95% confidence intervals were utilized. Heterogeneity were assessed by Q-square (v2 ) and I-square statistics (I²). Meta-analysis with forest plot was performed using Review Manager Version 5.3. Results Remission of diabetes was achieved in 69 out of 94 patients (73%) in four studies included in the analysis (OR = 79.07, 95% CI 12.36, 506.3). Decrease in glycosylated hemoglobin, fasting blood sugar, body mass index, weight, total cholesterol, triglycerides and increase in HDL was greater in the surgical arms of all the included studies. Conclusion Bariatric surgery is a rapid, effective and sustainable treatment option for the resolution of type 2 diabetes mellitus even among mildly obese patients. It is effective in improving or resolving diabetes- and obesity-related diseases such as dyslipidemia.