The Venom Duct of Conus geographus: Some Biochemical and Histologic Studies

Lourdes  Cruz,; Erlina  S. Pali,; Oscar  M. Tangco,

The Venom Duct of Conus geographus: Some Biochemical and Histologic Studies

Erlina S. Pali | Oscar M. Tangco | Lourdes Cruz

Abstract:

The toxicity pattern and biochemical properties of the contents of successive sections of the venom ducts of Conus geographus were determined. both lethal and paralytic activities were observed to increase towards the posterior duct region. In all segments, toxicity was found to be mainly associated with the soluble rather than the granular fraction. Data from SDS gel electrophoresis and thin layer gel chromatography suggest that the lethal activity of the venom is due mainly to the low molecular weight components found in the soluble fraction of the posterior segments.

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