This study used interactive strategies to improve the vocabulary skills of 177 grade 3 pupils of Jose Rizal University, in order to answer the following questions: (1) What are the factors affecting the respondents’ vocabulary skills?; (2) What interactive strategies did the grade 3 pupils prefer?; and (3) Is there a significant difference between the two assessments given to the respondents after the implementation of the interactive strategies in their classes? In the pre-intervention stage or process, the level of the vocabulary skills of the respondents was measured. A survey was also conducted to identify factors that affect respondents’ acquisition of language. Different strategies were then used by the teachers like the memory and the social strategies. The post-intervention stage was conducted, using all the strategies within the period of the study. The study habits and interest of the learners were found to be the factors affecting the acquisition or improvement of vocabulary skills of the respondents. The social strategies were assessed by the grade 3 pupils as very effective, and the vocabulary skills of the respondents improved after the interactive strategies were implemented.