This study aimed to design a monitoring system for hospital patients that would automatically measure and monitor body temperature, blood pressure, and heart rate conditions of the patients and send the data wirelessly to a personal computer located at the nurse station for the display. Specifically, it sought to test the functionality of the system, its features, and its capability of determining the three vital signs of the patients with regard to its monitoring system and wireless communication. Experimental development and descriptive method were employed in this study. The researchers developed a prototype through a series of research and experimentation and the device’s efficiency were assessed by 43 purposively chosen evaluators composed of five (5) doctors, five (5) hospital nurses, five (5) patients, five (5) caretakers, five (5) clinical instructors, two (2) school nurses, five (5) nursing students, five (5) engineering students and six (6) engineering faculty. A functionality test comparing the system with the traditional instruments used for measuring the three vital signs was also done to determine the level of functionality. Results from the evaluation revealed that the evaluators rated the system very high in terms of its capability of measuring the three vital signs, the level of wireless transmission, the graphical output, and the level of the system’s audio and visual alarm for critical levels. Functionality test data showed that the system’s functionality in terms of its sensors is comparable with the traditional instruments used.