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HomeRoot Gatherersvol. 5 no. 1 (2013)

Potential Analgesic and Anti-Inflammatory Properties of the Dried Leaf Extract of Lagnub (Ficus septica)

Cherrie G. Muaña | Ma. Liza L. Belga | Ruby Jean C. Castillo | Keith Ian A. Dimaano | Rovie Lae M. Fuentes | Dan David A. Odasco

 

Abstract:

The study was conducted to assess the potential analgesic and anti-inflammatory properties of the dried leaf extract of Lagnub (Ficus septica). Pharmacologic efficacy was based on the folkloric claim of Ata Matigsalog tribe in Arakan, North Cotabato. Primarily, acute oral toxicity was determined by administering 300 and 2,000 mg/kg doses, respectively to the mice. Result categorized as non-toxic due to no observable sign of toxicity in the test animals after 24 hours. The plant was also being tested on acetic writhing assay for analgesic property. Noticeable effects between 79.34 to 316.22 mg/kg as no observable writing of the test animals were recorded thus, confirming the analgesic effect of the left extract. Likewise, carageenan-induced rat paw edema was conducted to attain the anti-inflammatory property. All of the dose levels were able to reduce the paw thickness of the test animals. This plant material has preliminary effect as an anti-inflammatory agent thus, further tests must be conducted.