The rise of Manny Pacquaio in 1998 revived the popularity of boxing in the Philippines. But such popularity is only limited to men because women are still not interested in boxing as a sport. With this, the researcher identified the knowledge of female university students about the nature, rules and trainings in boxing and its relationship to the interest of female university students in boxing. This study employed a descriptive-correlation design wherein 394 female students became the respondents coming from the four universities in Davao City. The survey questionnaire was validated by experts in the field of sport, and reliability tested with an internal consistency correlation value of 0.67 and a Cronbach’s value of 0.88, respectively. Based on the result, most of the respondents had knowledge about the training in boxing but they were not interested in boxing as a sport. No significant relationship was found between the knowledge and interest of the respondents in boxing.