The trace elements cadmium, copper, and lead have caused major human health problems in several parts of the world. Concerns over such incidents have prompted numerous investigations into the metabolism and toxic effects of these three toxic and harmful trace elements. Cadmium, copper and lead are usually used for industrial purposes and they are the major ingredients in certain products such as paints, fertilizers and cigarettes. Banana plantation farmers are usually exposed to different chemicals which make them highly susceptible to exposure of these harmful heavy metal elements. A prospective descriptive-quantitative design was utilized in the determination of the levels of cadmium, copper and lead in blood samples from banana plantation workers in Cuambugan, Tagum City. Thirty-five farmers aged between 19-46 years old were randomly selected. Blood samples were collected and tested using flame atomic absorption spectrophotometer. Results of the study showed that the banana plantation workers with the age range of 42-48 years old have the highest mean level of cadmium (0.33ppm) and copper (0.79ppm). Lead levels were high in age-group 31-36 years old with the highest mean level of 6.51ppm. These values were considerably high and have exceeded the tolerable level established by the Occupational Safety and Health Hazard.