The education system in the Philippines is continually developed to provide a better and improved quality education. Entailed with the changes are the requisites students must attain to be able to keep up with the educational demands which may cause inevitable stress. The stress experienced by students may stem from various factors which was measured in this study. This study determined whether or not students’ level of stress and their academic performance have significant relationship. A descriptivecorrelation design was used involving 124 third year college students from the Bonifacio Campus of University of the Immaculate Conception. The study was conducted during the preliminary term of the second semester of the academic year 2017-2018. The results revealed that students were mostly stressed out due to their lifestyle and perceived academic stress. Furthermore, these results suggest that students’ academic performance is influenced by their stress.