Rising environmental concerns led to the emergence of the concept of green chemistry in the last half of the twentieth century. Integration of Green Chemistry education at the undergraduate level is said to be a key to adopting sustainable practices leading to a sustainable society. The study was conducted to determine the “Green Chemistry Perspective among Stem 12 Senior High School Students in the Province of Abra.” The descriptive correlational research design was used to look into the influence of the profile, knowledge, attitudes, and practices of the respondent towards green Chemistry. A total of 103 students participated in the survey. Data collected were analyzed using SPSS Software (version 20). Correlation result shows that gender is significantly correlated to students’ level of knowledge in green chemistry (-0.207). The correlation coefficient of 0.214 means that membership in an organization is also significantly related to students’ level of knowledge in green chemistry. Students participating in various environmental activities also tend to have a higher level of knowledge of green chemistry with a correlation coefficient of 0.297. The student’s level of attitude towards green chemistry is also significantly related to students’ level of knowledge in green chemistry.