This study sought to determine the effects of sweet sorghum (Sorghum bicolor, Linn.) syrup on the blood glucose level in alloxan-induced diabetic mice. Specifically, it focused on the determination of initial and final blood glucose level of the white mice that were treated with table sugar as well as on the determination of the initial or fasting blood glucose level and final blood glucose level of the white mice that were treated with sweet sorghum syrup. Moreover, it also determined the significant difference between the final blood glucose level using the table sugar and sweet sorghum syrup. The subjects of the study were twelve (12) mice that were induced with alloxan monohydrate to become diabetic. Four (4) of the mice were under Group A (control) while the other four (4) mice (Group B) were treated with table sugar while the remaining four (4) mice (Group C) were treated with sweet sorghum syrup. The data were statistically analyzed using the Analysis of Variance (ANOVA) to test the differences among treatment means at 0.05 and 0.01 level of significance. Result of thorough data analysis showed that administration of table sugar and sweet sorghum syrup increased the blood glucose level of mice. However, table sugar has greater increase in blood glucose level than sweet sorghum syrup. This study also showed that the blood glucose levels of mice tend to return to the initial level after four hours of administration of treatments. Based on the salient findings of this study, it is recommended that another study of the same nature should be done and should use greater number of experimental animals as subjects of the study to minimize the percentage of errors.