Daniela Niccole Manzano | Sandra Paulene Mendoza | Edryd Psalm Logroño | Clyana Dhannereen Masangkay | Renei Beatriz Delos Reyes | Maria Carla F. Manzano | Enrique M. Manzano
This paper seeks to find a way to measure blood glucose levels in real time, in-situ, non-invasively, painlessly, and cost-effectively using matched LED pairs as photo-transmitter and photo-detector. The research demonstrated the feasibility of using the same high-intensity, narrow-beam transmitter LED as photo-detector, improving selectivity and sensitivity. Using a near-infrared LED (GaAlAs, 895 nm, 20mW, 8? half-power beam width), the following relationship between signal attenuation at the detector versus the glucose concentration in solution was obtained: = 0.004(NIR LED output Voltage) + 9.2707 with a very high Pearson’s Correlation Coefficient of +0.9985 and a coefficient of determination of 0.9971, highly correlated and highly linear.
1. O. Amir, et.al, “Continuous noninvasive glucose monitoring technology based on occlusion spectroscopy,” Journal of Diabetes Science and Technology, 1(4), 463-469, 2007.
2. C. Malchoff, et.al, “A novel noninvasive blood glucose monitor,” Diabetes Care 25(12), 2268-2275, 2002.
3. J. Pablico, E. Manzano, and M.C. Manzano, “An investigation on the use of infrared light for non- invasive phototransistor-based blood glucose measurements,” Physics Department, De La Salle University – Manila, thesis paper, 2015.
4. D. Sia, “Design of a near-infrared device for the study of glucose concentration measurements,” EE2BI6 Electrical Engineering Biomedical Capstones, paper 40, 2010.
5. A. Srivastava, et.al, “Blood glucose monitoring using noninvasive optical method: design limitation and challenges,” International Journal of Advanced Research in Electrical, Electronics and Instrumentation Engineering, 2(1), 615-620, 2013.
6. Y. Yu, K.D.Crothall, L.G. Jahn, and M.A. DeStefano, “Laser diode applications in a continuous blood glucose monitor,” Proc. SPIE, 4996, 268-274, 2003