The aim of this research was to determine the significant relationship between motivational factors and mentoring skills of 99 faculty members of higher education institutions in Digos City. Employing descriptive correlation method of research, validated questionnaires as research instruments, mean, Pearson r and multiple regression as statistical tools, results revealed that both the levels of motivational factors and mentoring skills of the respondents were described as high. There was a significant relationship between motivational factors and mentoring skills of the respondents. School administrators should be sensitive always to the teaching needs of teachers to enable them to work effectively as educators. Since interpersonal relation was found as the best predictor of mentoring skills school activities that enhance interpersonal relationships should be initiated. Further studies on mentoring skills where students are the respondents are warranted.