HomeUIC Research Journalvol. 18 no. 2 (2012)

Quality and Safety Evaluation of Commercial Mangosteen (Garcinia mangostana Linn.) Capsule

Ma. Eva C. San Juan | Razle R. Alagos | Ruiza R. Alocelja | Ruel S. Manluyang Jr.

Discipline: Health



Many herbal food supplements today are being sold in market and most popular among them is the commercial mangosteen (Garcinia mangostana Linn.) capsule. With the present scenario, this study focused on ensuring the quality of commercial mangosteen (Garcinia mangostana Linn.) capsule being sold in the market for consumer’s safety. Based on results of experimentations, the sample of commercial mangosteen capsule passed all the tests conducted. The disintegration time using water and simulated gastric fluid as a solvent was within the 30 minutes specification set by 22nd edition of USP XXII/NF XVII, which was at 21.88 minutes and 10.83 minutes, respectively. Result also revealed that commercial mangosteen capsule was more soluble in simulated gastric fluid when compared to water since, in the first test, all the capsule disintegrated completely within 30 minutes at a lower mean disintegration time and the residue left after the experimentation was lesser. For microbial limit tests, the Aerobic Plate Count (CFU/g) was 540 (normal limit - 104), Yeast (CFU/g) at 135 (normal limit -103), and Molds (CFU/g) at 10 (normal limit- 103). Lastly, for heavy metal load, Cadmium (ug/g) has <0.05 (normal limit - 0.3) and Lead (ug/g) has 2.73 (normal limit – 10). All results conformed to FDA Guidelines. Therefore, commercial mangosteen capsule has met the minimum quality control standard and is safe for human consumption based on the 22nd edition of USP XXII/NF XVII specifications and FDA Guidelines.