The topic of “Occupational Health and Safety” has been focused on as a main function of Human Resource Management. Occupational safety and health covers a wide range of activities and functions. This research paper looks at what health and safety refers to, why research should be conducted into it, and how it is helpful for organizations and employees, and for the human resource management as a whole. It is followed by a discussion on Occupational Safety and Health with emphasis on several sub-topics, which are elaborated upon. Light will be shed on various OSH issues, and how Human Resource Management deals with them. Besides, legal requirements for health and safety rules will be looked into, with a focus on proposed solutions to the mentioned issues. A comparison of safety measures in the global context will be compared with safety measures in the local context, to understand how different organizations handle safety. There are several recommendations for business practice as well as their implications. What is more, there are suggestions for future business research, especially in the area of Human Resource Management.