Home⇛The PCMC Journal⇛vol. 16 no. 2 (2020)

Clinical Features, Outcomes and Risk Factors for the Development of Acinetobacter Baumannii Infection among Newborns in Philippine Children’s Medical Center

Jennifer M. Relucio | Sheila Ann D. Masangkay

Discipline: medicine by specialism

 

Abstract:

OBJECTIVES: To determine the risk factors, clinical features, and outcomes of newborns in a tertiary care hospital who developed Acinetobacter baumannii infection. METHODOLOGY: A retrospective case control study was performed, comparing each case of newborn infected with Acinetobacter baumannii to two uninfected controls. RESULTS: Ninety charts were reviewed, comprising 30 cases and 60 controls. Risk factors (use of total parenteral nutrition, prior antibiotic use, presence of a central line, mechanical ventilation and intubation, blood transfusion, surgical procedure, intensive care unit admission and presence of a co-morbidity) were noted to be significantly associated with the development of A. baumannii infection (p value <0.001). A. baumannii infection manifests more commonly as fever, respiratory distress, leukocytosis, and thrombocytopenia. CONCLUSIONS: Acinetobacter baumannii is associated with certain risk factors that increase the likelihood for its perpetuation and acquisition. The increasing number of multi-drug resistant strains of A. baumanni signifies the need to focus on certain issues as infection control and the conscientious use of antibiotics in newborns.



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