Clinical-based motivation is an effective way in teaching physics of the fifty third year Bachelor of Science in Nursing students of the College of Health Sciences, University of Northern Philippines, Vigan City. The study aimed to determine the relevance and effects of clinical-based motivation in physics performance. The study utilized the quasi-experimental design specifically the non-equivalent control group pretest-posttest design without the possibility of the randomization process. The students in the experimental group were found strong in the topics scalar and vector quantities, force, work and energy but weak in measurement. In the control group, they were weak in all the topics. There was significant difference between the posttest mean scores of the experimental and
control groups. The physics performance of students exposed to clinical-based motivation is significantly higher than those in the traditional method.