HomeHealth Sciences Journalvol. 15 no. 1 (2026)

The Accuracy of Ankle-Brachial Index Determination Using the Stethoscope to Screen for Peripheral Arterial Disease Among Adults with Type 2 Diabetes Mellitus in Iloilo City

Discipline: medicine by specialism

 

Abstract:

Introduction Peripheral arterial disease (PAD) is a common macrovascular complication of type 2 diabetes mellitus (T2DM) and is associated with increased cardiovascular morbidity and mortality. The ankle-brachial index (ABI) is a simple, non-invasive method for detecting PAD; however, Doppler devices are not always available in primary care and resource-limited settings. This study aimed to determine the diagnostic accuracy of ABI measurement using a stethoscope compared with the Doppler method among adults with T2DM. Methods A diagnostic accuracy study was conducted among 200 adults with T2DM recruited through convenience sampling from a private outpatient clinic in Iloilo City. ABI measurements were obtained using both the stethoscope and Doppler methods. An ABI of ≤0.90 was considered indicative of PAD. Diagnostic accuracy measures, including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), overall accuracy, and agreement, were calculated. Results The prevalence of PAD was 30.5% using the stethoscope method and 35.0% using the Doppler method. Compared with Doppler ABI, the stethoscope method demonstrated an overall accuracy of 94.5%, sensitivity of 85.7%, specificity of 99.2%, PPV of 98.4%, and NPV of 92.8%. Agreement between the two methods was excellent (Cohen’s κ = 0.88, p < 0.001). Conclusion Stethoscope-based ABI determination demonstrated high diagnostic accuracy and excellent agreement with Doppler ABI. Given its low cost, accessibility, and non-invasive nature, it may serve as a practical screening tool for PAD among adults with T2DM, particularly in primary care and resourcelimited settings where Doppler devices are unavailable.



References:

  1. International Diabetes Federation. IDF Diabetes Atlas. 10th ed. Brussels: International Diabetes Federation; 2025. Available from: https://diabetesatlas.org
  2. Thiruvoipati T, Kielhorn CE, Armstrong EJ. Peripheral artery disease in patients with diabetes: epidemiology, mechanisms, and outcomes. World J Diab 2015;6(7):961-9.  doi:10.4239/wjd.v6.i7.961
  3. Dans AL, Morales DD, Velandria F, Abola TB Jr, Roxas A Jr, Punzalan FER, et al. National Nutrition and Health Survey (NNHeS): atherosclerosis-related diseases and risk factors. Philipp J Intern Med 2005;43(5):103-15.
  4. Hirsch AT, Criqui MH, Treat-Jacobson D, Regensteiner JG, Creager MA, Olin JW, et al. Peripheral arterial disease detection, awareness, and treatment in primary care. JAMA 2001;286(11):1317-24. doi:10.1001/jama.286.11.1317.
  5. Parwani D, Ahmed MA, Mahawar A, Gorantla VR. Peripheral arterial disease: a narrative review. Cureus 2023;15(6):e40267. doi:10.7759/cureus.40267.
  6. American Diabetes Association. Toolkit No. 25: All About Peripheral Arterial Disease. Alexandria (VA): American Diabetes Association; 2009. Available from: https://professional.diabetes.org/sites/dpro/files/2024-01/all_about_peripheral_arterial_disease_0.pdf
  7. Mueller T, Hinterreiter F, Poelz W, Haltmayer M, Dieplinger B. Mortality rates at 10 years are higher in diabetic than in non-diabetic patients with chronic lower extremity peripheral arterial disease. Vasc Med 2016;21(5):445-52. doi:10.1177/1358863X16643603.
  8. Libby P, Bonow RO, Mann DL, Zipes DP, editors. Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia (PA): Saunders Elsevier; 2007.
  9. Ugwu E, Adeleye O, Gezawa I, Okpe I, Enamino M, Ezeani I. Predictors of lower extremity amputation in patients with diabetic foot ulcer: findings from MEDFUN, a multicenter observational study. J Foot Ankle Res 2019;12:34. doi:10.1186/s13047-019-0345-y.
  10. Rhee SY, Guan H, Liu ZM, Cheng SWK, Waspadji S, Palmes P, et al. Multi-country study on the prevalence and clinical features of peripheral arterial disease in Asian type 2 diabetes patients at high risk of atherosclerosis. Diab Res Clin Pract 2007;76(1):82-92. doi:10.1016/j.diabres.2006.07.029.
  11. Donohue CM, Adler JV, Bolton LL. Peripheral arterial disease screening and diagnostic practice: a scoping review. Int Wound J 2020;17(1):32-44. doi:10.1111/iwj.13223.
  12. Pleo S, Cresencio JV, Alajar E. Frequency of peripheral arterial disease diagnosed by measurement of the ankle- brachial index among diabetics with no symptoms of intermittent claudication. J ASEAN Fed Endocr Soc 2012;27(2):209.
  13. Shu J, Santulli G. Update on peripheral artery disease: epidemiology and evidence-based facts. Atherosclerosis 2018;275:379-81. doi:10.1016/j.atherosclerosis.2018.05.033.
  14. Pabon M, Cheng S, Altin SE, Sethi SS, Nelson MD, Moreau KL, et al. Sex differences in peripheral artery disease. Circ Res 2022;130(4):496-511. doi:10.1161/CIRCRESAHA.121.320702.
  15. Setacci C, de Donato G, Setacci F, Chisci E. Diabetic patients: epidemiology and global impact. J Cardiovasc Surg (Torino) 2009;50(3):263-73.
  16. Carmo GAL, Mandil A, Nascimento BR, Arantes BD, Bittencourt JC, Falquetto EB, et al. Can we measure the ankle-brachial index using only a stethoscope? A pilot study. Fam Pract 2009;26(1):22-6. doi:10.1093/fampra/cmn086.