HomePhilippine Journal of Veterinary Medicinevol. 41 no. 2 (2004)

Penile Growth in Fetal Alcohol Syndrome of Mice

Josephat E. Onu | Daniel N. Ezeasor | Emeruwa C. Ihemelandu | Nnaemeka Ndondo

Discipline: Veterinary Medicine



An investigation was conducted to determine the effect of maternal alcohol consumption on the growth of penis of neonatal mice. Three groups of mice were used. The offspring of group 1 served as control while those of groups 2 and 3 were given 30% ethanol (v/v) prenatally and pre-and postnatally, respectively. At 3, 4, 5 and 6 weeks of age, 10 male offspring were randomly selected from each of the three groups and sacrificed. After the sacrifice, the penis were dissected out and their weights determined. The result of the investigation showed reduction in the weight of penis of the offspring exposed to alcohol when compared with the controls. The result also showed that the penis of the offspring exposed to alcohol had greater growth rates. The investigation has therefore demonstrated that maternal alcohol consumption during prenatal and pre- and postnatal periods affects the growth of the penis and that there was an attempt by the alcohol exposed penis to catch up growth with the controls.