HomePhilippine Journal of Veterinary Medicinevol. 42 no. 2 (2005)

Effect of Ivermectin and Praziquantel-Abamectin on Gastrointestinal Helminths of Chickens

Billy P. Divina | Michael Remil G. Amparo | Edward F. Barroga

Discipline: Veterinary Medicine

 

Abstract:

One hundred twenty eight sexually mature backyard-raised native chickens, which were naturally infected with gastrointestinal (GI) helminths, were allocated randomly into four groups with two replicate each. The efficacy of 1% ivermectin (IVM) (single dose, 0.2 ml/kg BW PO) and praziquantel-abamectin (PZQ-ABM) (12.5 mg praziquantel-0.5 mg abamectin/tablet) at the ratio of 0.25 tablet/bird PO and administered once and twice with two-week interval were determined based on fecal egg count reduction (FECRT) and controlled test. FECRT result shows that IVM had 89.3 and 55.8% efficacies against ascaridia/Heterakis spp. and Capillaria sp., respectively whereas PZQ-ABM had 78.6 and 53 3% efficacies-against the same nematodes, respectively, when given once and had 58.3 and 61.6% efficacies when given twice. Based on controlled test IVM had 100% efficacy against Capillari sp. but ineffective against other nematodes. PZQ-ABM(single-dose) was ineffective against Heterakis sp. and Tetrameres sp. but had 91.0 and 84.2% efficacies against Raillietina spp. and Gongylonema sp., respectively and 100% against Ascaridia, Capillaria sp. and Dispharynx spiralis. When given twice, it had 92.2-100% efficacies against the above GI helminths. This study provides evidence that IVM may be used for the effective control of Capillaria sp. in native chickens and that PZQ-ABM was highly effective against a wider species of helminths, including tapeworms, particularly when it is given twice.