HomePhilippine Journal of Veterinary Medicinevol. 42 no. 2 (2005)

Cytochrome P450 Aromatase and Estrogen Receptors (ERα and β) in the Testis of the Philippine Warty Pig (Sus philippensis

Bella C. Cruzana | Grace D. De Ocampo | Motoki Sasaki | Nubou Kitamura | Junzo Yamada

Discipline: Veterinary Medicine



The site of aromatization and estrogen actions in the testes of the wild boar were investigated by immunolocalizaton of cytochrome P450 aromatase (P450arom) and estrogen receptors (ERα and ERβ). Based on the present result, aromatization occurs in the interstitial cells in the testes of wild boar. Moreover, estrogen action is mediated by two estrogen receptors. ERα and ERβ. Estrogen receptors α and β were localized m the interstitial cells of testes, suggesting an autocrine and paracrine action in this organ.