The quality of instruction depends on a large extent of the capability, the strength, and the excellence of the faculty. For the faculty to perform their roles and fulfill their responsibilities, Colleges must first show that they understand what the faculty needs and values most. The purpose of this descriptive study was to determine the professional development needs and priorities pertaining to teaching and learning of the college faculty (n=71) of La Salle University to guide the administrators and faculty in crafting enrichment activities. Sixty-three percent of the 113 teachers completed a survey instrument. Calculated means and frequency-percentage distribution describes the prioritization of in-service needs while weighted means determine the performance of the college faculty as appraised by the students. The results of this study showed one-thirds of the teacher-respondents as new to the teaching profession while 69% have more than three years of teaching experience. The study concludes that the colleges vary in their needs for professional development. However, there are areas common to almost all colleges. Their top priority need for classroom management is ending the class on time. For the evaluating students’ learning, the top priority is mastery of the subject matter. For evaluating students’ learning, the priority is constructing questions that cover topic discussed.