Philippine E-Journals

The Effectiveness of Commercially-Prepared Anti-Dandruff Shampoos in the Treatment of Malassezia globosa

Rey Marvin Gastador | Joshua Asha Liquete | Janderreck Lane Manalo | Shierina Masilang | Garrett Paltao | Kristine Leanne Sarmiento

Discipline: Chemistry

 

Abstract:

This study determined the degree of effectiveness of five commercially-prepared anti-dandruff shampoos in the treatment of Malassezia globosa, one of the dandruff-causing organisms. Specifically, it identified which of the five shampoos with the corresponding active anti-dandruff components: zinc pyrithione, zinc vitanol, climbazole and ketoconazole have the best inhibitory effect on Malassezia globosa.

 

The five shampoos were labeled according to anti­dandruff ingredient. Brands A and C contain zinc pyrithione, Brand B – zinc vitanol, Brand D – climbazole, and Brand E – ketoconazole. Each of the shampoos were diluted in proportions of 1:2, 1:4 and 1:8 and were tested on cultured Malassezia globosa in SDA (

This study determined the degree of effectiveness of five commercially-prepared anti-dandruff shampoos in the treatment of Malassezia globosa, one of the dandruff-causing organisms. Specifically, it identified which of the five shampoos with the corresponding active anti-dandruff components: zinc pyrithione, zinc vitanol, climbazole and ketoconazole have the best inhibitory effect on Malassezia globosa.

 

The five shampoos were labeled according to anti­dandruff ingredient. Brands A and C contain zinc pyrithione, Brand B – zinc vitanol, Brand D – climbazole, and Brand E – ketoconazole. Each of the shampoos were diluted in proportions of 1:2, 1:4 and 1:8 and were tested on cultured Malassezia globosa in SDA (Sabaraud Dextrose Agar) media for seven days. The zones of inhibition for each dilution were measured and compared.

 

The study showed that five brands of commercially-prepared anti-dandruff shampoos exhibited different degrees of effectiveness in inhibiting the growth of Malassezia globosa. The brand which contains ketoconazole has the largest zone of inhibition while the shampoo with climbazole has the smallest. This implies that ketoconazole is the most effective in the treatment of Malassezia globosa while climbazole is the least effective. Further, the results revealed that the degree of concentration of the active ingredient in an anti-dandruff shampoo is directly proportional to its effectiveness.

 

) media for seven days. The zones of inhibition for each dilution were measured and compared.

 

The study showed that five brands of commercially-prepared anti-dandruff shampoos exhibited different degrees of effectiveness in inhibiting the growth of Malassezia globosa. The brand which contains ketoconazole has the largest zone of inhibition while the shampoo with climbazole has the smallest. This implies that ketoconazole is the most effective in the treatment of Malassezia globosa while climbazole is the least effective. Further, the results revealed that the degree of concentration of the active ingredient in an anti-dandruff shampoo is directly proportional to its effectiveness.