The study attempted to evaluate the Comfort Behavior Scale as a pain assessment tool for infants. Using the evaluative-descriptive type of research, the administrability, scorability and usability of the tool were evaluated locally to propose its utilization at the chosen locale of the study, the Quezon Medical Center (QMC)- Pediatric Ward. To achieve this purpose, factors that may influence the evaluation of the tool were determined. The study evaluated the adapted assessment tool (Comfort Behavior Scale) using the researcher devised questionnaire through pre test and post test. The respondents were chosen randomly. Pre-tests were given to them through utilization of the adapted assessment tool without orientation about the tool. While post tests were given to the respondents after they had utilized the tool for certain period of time. Frequency, weighted average mean and t-test were used in the treatment of data. The findings of the study revealed that respondents strongly agreed that the Comfort Behavior Scale can be easily administered, scored, and used; and they strongly agreed that the use of Comfort Behavior Scale can help improve the services offered by the QMC’s Pediatric Ward.