During the field evaluation of the potential low-dose metaldehyde formulation against golden apple snail (GAS), Pomacea canaliculata (Lamarck), we consistently observed that only microplots treated with niclosamide 250EC had adverse effects on the growth and establishment of direct-seeded rice (DSR). This prompted us to verify field observations under screenhouse tests at the PhilRice-Central Experiment Station in Nueva Ecija, Philippines. Commercial synthetic molluscicides such as niclosamide 250EC and metaldehyde are used among lowland irrigated transplanted rice farmers in Asia. However, niclosamide 250EC is preferred over metaldehyde formulations because of its "quick-kill" action on GAS. Unfortunately, niclosamide 250EC is lethal to nontarget beneficial water-borne organisms such as frogs, fish, etc. Hence, in the future, it is important for rice farmers to practice ecologically sustainable GAS management options that are safe to the rice crop, their health, and their environment.