The first detection of caprine arthritis encephalitis (CAE) in goats in Eastern Visayas was documented using ELISA test. The experimental farms were chosen from the available secondary data of incoming animals from outside sources, either imported from other countries or from neighbouring regions. Farm production and management systems and practices were recorded. A total of 660 serum samples were collected from goats and tested for CAE antibodies. Twenty (20) serum samples, representing 3.03%, were found positive for CAE antibodies. Positive samples were recorded from commercial and government farms, none from backyard farms. Clinical signs of sero-positive animals include paralysis, head twisting and mastitis. Results of the study prompted enforcement of regulatory measures that entry of goats to the region must have complied with CAE-free certification from the point of origin. The Regional Advisory Committee on Disease Control and Emergency strongly recommended the immediate issuance of a regional advisory on CAE to the Department of Agriculture-Regional Field Unit N0. 8. Extensive surveillance and monitoring of incoming imported goats from other regions and abroad should also be strictly followed to prevent domestic transmission. Communication of results and advocacy with LGUs and stakeholders on the prevention and control of CAE in the region were given priority.