Reports of increasing anthelmintic resistance to chemical dewormers used in goat farming necessitate research on alternative anthelmintics. The study was conducted to evaluate the efficacy of jackfruit and tamarind leaves decoction as alternative anthelmintics and to determine the mean effective dose (ED50) of the different concentrations against larval development of gastrointestinal nematodes in goats. Fecal slurries with prepared decoctions at different concentrations were inoculated with 100 nematode eggs, then incubated at room temperature for seven days. Larvae were collected, enumerated and identified. Four genera of gastrointestinal nematodes were identified, namely, Trichostrongylus spp., Oesophagostomum spp., Haemonchus spp. and Bunostomum spp. Results showed that at increasing concentrationsof jackfruit and tamarind leaves decoctions, the number of larvae killed increased. Both jackfruit and tamarind decoctions showed high efficacy in killing nematode larvae at high concentrations. ED50 was at 40% concentration for both decoctions. The results suggest that decoctions of jackfruit and tamarind leaves can be used as anthelmintics in goats.