HomePhilippine Journal of Veterinary Medicinevol. 52 no. 1 (2015)

Immunohistochemical Detection of Serotonin in the Small and Large Intestines of the Domestic Cat (Felis catus L.) (Carnivora: Felidae)

Rodel Jonathan S. Vitor Ii, Dvm | Juan Carlos C. Dimayuga | Rizza Mae L. Labadan | Melanie Anne M. Atienza

Discipline: Anatomy

 

Abstract:

Immunohistochemical detection of serotonin was performed in the small (duodenum, jejunum, ileum) and large intestines (cecum, colon and rectum) of 20 (10 male and 10 female) 2-year old domestic cats (Felis catus L.). In both organs, serotonin was observed to be reactive in the lining epithelium, enterochromaffin cells in the crypts of Lieburkuhn, smooth muscle fibers in the lamina propria, lamina muscularis mucosae and tunica muscularis, blood vessels in the lamina propria, tunica submucosa and serosa, Brunner’s glands in the duodenum, Meissner’s plexus in the tunica submucosa, myenteric plexus in the tunica muscularis and the lining epithelium of the tunica serosa. One main difference that has been observed is the absence of serotonin reactivity in the goblet cells. Presence of serotonin in the different segments of the intestines suggests that it can modulate the physiological processes of the intestines by exerting its effort on the different target cells.