Engrossing in playing Defense of the Ancients (DOTA 1) has become a huge dilemma to the society. The popularity of the said game is at its peak, that even some students were reported to have flunked in school due to negligence from the academic responsibilities. With the increasing prevalence of the impact of playing DOTA 1, learners in schools need to increase their literacy and proficiency in any subject area particularly in Mathematics. This quantitative-qualitative research aimed to determine the relationship between college students’ attitude towards playing DOTA 1 and their Trigonometry proficiencies. A researcher-made questionnaire and actual interviews were used to determine the level and views of college students’ attitude towards playing DOTA and Trigonometry proficiencies. The weighted mean, Pearson r and standard deviation were the statistical tools used in this study. The results of the gathered data revealed that the level of attitude of the college students towards playing DOTA 1 was high and the level of trigonometry proficiencies of the college students was good. Furthermore, there was a significant relationship between college students’ attitude towards playing DOTA 1 and trigonometry proficiencies. On the other hand, the students’ views with respect to the effects of playing DOTA 1 and their trigonometry proficiencies were established with more effective and positive remarks. They added that playing DOTA 1 had contributed positive improvements towards their factual learning, learning behaviors, and most especially, changes in personality.