Most of the construction projects in Fezzan, Libya were not delivered on the agreed time and this had been a perennial problem. The delay was linked to the different factors affecting the performance of construction projects and varied from one country to another. This study was conducted to make a comparative assessment of the selected factors on construction projects in Fezzan, Libya. This quantitative study utilized the descriptive survey and descriptive comparative research designs. A postal questionnaire survey was administered to 54 companies located in the Southern part of Libya (Fezzan), 40 were local and 14 were foreign companies. The same questionnaire was administered to 26 managers, 15 vice-managers and 13 consultants. Frequency count, percentage, weighted mean, standard deviation, t-test and ANOVA were the statistical tools used in the study set at 0.05 level of significance. Findings of the study revealed that health and safety factors were very important and a significant difference was manifested when grouped according to the type of company and position, while there was none when grouped according to the type of projects and size of the company.