This study focused on determining the effect of integrating QuexHub (mobile learning application) in the academic performance of students in Physical Science in the new normal class room context. A quasi-experimental research method was employed in the study. The control group utilized DepEd Self-learning Modules (SLMs), while the experimental class used the QuexHub mobile learning app and SLMs. Both of the groups underwent a pre-and post-examination using the SDO-validated test to measure their academic performance. Pretest and post test scores were collected and analyzed. The analysis revealed that after the implementation, the control group advanced academically and got a satisfactory academic performance while the experimental group made a significant progress and obtained a very satisfactory grade. Thus, there is a significant difference in academic performance between the two groups which confirms that the experimental group's use of QuexHub was significantly effective. This result suggests that the use of the QuexHub mobile learning platform enhanced the use of SLMs in order to optimize the teaching-learning process in new normal education. Hence, schools should invest with innovative ways to provide students the access to technology for educative advancement.